Competition Between miRNA Families Extends Beyond the miRNA Seed Sequence Region

In a recent publication in Nucleic Acids Research, Laski, Brümmer, Lucic, and colleagues demonstrate that miRNAs from the miR-17 and let-7 families can compete for mRNA target sites involving a non-canonical miRNA-target interaction. miRNAs are generally known to recognize and bind target sites complementary to six- to eight-nucleotides located at the 5′ end of the […]