What kind of analysis do we do
Methods:
- LC-MS/MS
- Lipidomics
- (Un)targeted metabolomics
Molecular insights into sex-specific metabolic alterations in Alzheimer’s mouse brain using multi-omics approach
In this publication, we performed multi-omics factor analysis (MOFA) to identify the shared factors between lipidomics, metabolomics and proteomics datasets in an Alzheimer mouse model. Strong differences were found between male and female mice that carried 3xTg-AD (three mutant alleles; homozygous for the Psen1 mutation and homozygous for the co-injected APPSwe and tauP301L transgenes)
